Avidity Model Pack
What's Included?
Applied BioMath Assess™ Avidity Model Pack includes models covering both soluble and membrane ligand pharmacologies.
- Monospecific Anti-Receptor with Avidity (4-Compartment)
- Four-compartment model of avid bivalent antibody binding to membrane receptor.
- Bispecific Anti-Ligand x Anti-Receptor with Avidity (4-Compartment)
- Four-compartment model of avid bivalent antibody binding to soluble ligand and membrane receptor
- Bispecific Anti-Receptor x Anti-Receptor with Avidity (4-Compartment)
- Four-compartment model of avid bivalent antibody binding to two different membrane receptors
- Bispecific Anti-Receptor x Anti-Ligand with Membrane Ligand x Receptor Competitor with Avidity (4-Compartment)
- Four-compartment model of avid bivalent antibody binding to soluble ligand and membrane receptor with a membrane receptor and membrane ligand competitor
- Bispecific Anti-Receptor x Anti-Receptor with Membrane Ligand x Soluble Ligand Competitor with Avidity (4-Compartment)
- Four-compartment model of avid bivalent antibody binding to two different membrane receptors with one membrane ligand and one soluble ligand competitor
- Bispecific Anti-Receptor x Anti-Receptor with Membrane Ligand x Membrane Ligand Competitor with Avidity (4-Compartment)
- Four-compartment model of avid bivalent antibody binding to two different membrane receptors with two membrane ligand competitors
- Monospecific Anti-Receptor with Membrane Ligand Competitor with Avidity (4-Compartment)
- Four-compartment model of avid bivalent antibody binding to membrane receptor and membrane ligand competitor
Figure 2: Model Parameters
Each model in Applied BioMath Assess™ Avidity Model Pack has a unique set of parameters, a sample of which is shown here, based on the model pharmacology and number of compartments. More details on the full list of parameters are available upon request. In the app, each parameter contains a default value based on expansive literature searches and references.
Additional Model Packs
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Cell Engager Model Pack: models for solid tumors, in-vitro experiments, and solid tumors with 2 cell types.
Protein Degrader Model Pack: 4 models covering in vivo and in vitro models of PROTAC and Molecular Glue Degrader pharmacologies.