Protein Degrader Model Pack
What's Included?
Applied BioMath Assess™ Protein Degrader Model Pack includes 4 models covering in vivo and in vitro models of PROTAC and Molecular Glue Degrader pharmacologies.
- PROTAC degrading an intracellular protein in vitro (beta)
- An in vitro model of a PROTAC targeting and degrading intracellular proteins
- MGD degrading an intracellular protein in vitro (beta)
- An in vitro model of a molecular glue degrader targeting and degrading intracellular proteins
- PROTAC degrading an intracellular protein in vivo (beta)
- An in vivo model of a PROTAC targeting and degrading intracellular proteins
- MGD degrading an intracellular protein in vivo (beta)
- An in vivo model of a molecular glue degrader targeting and degrading intracellular proteins
Insights on Molecular Glue Degraders
Hear from Josh Apgar, PhD, Co-founder and CSO at Applied BioMath as he discusses how modeling approaches can help address the challenges of molecular glue drug development.
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Figure 2: Model Parameters
Each model in Applied BioMath Assess™ Protein Degrader Model Pack has a unique set of parameters, a sample of which is shown here, based on the model pharmacology and number of compartments. More details on the full list of parameters are available upon request. In the app, each parameter contains a default value based on expansive literature searches and references.
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Avidity Model Pack: models covering both soluble and membrane ligand pharmacologies
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