Early Feasibility Assessment: A Method for Accurately Predicting Biotherapeutic Dosing to Inform Early Drug Discovery Decisions
Published in Frontiers in Pharmacology
Two heads are better than one: current landscape of integrating QSP and machine learning
Published in the Journal of Pharmacokinetics and Pharmacodynamics
Early Feasibility Assessment
In this case study, our partner was at the target selection stage for a bispecific agent that would hopefully work across four potential indications. They had confirmed one target, the anchor epitope (Target A), but were undecided as to the second target (Target B); based on the biology of their indications, they had 90 potential targets from which to choose, all with equally compelling biology as the project was very early.